A case report of subclinical primary aldosterone complicating with subclinical Cushing syndrome and literature review

Abstract

This case reports a rare subclinical primary aldosteronism complicated with subclinical Cushing’s syndrome. A 41-year-old female patient was admitted for adrenal incidentaloma, had no clinical manifestations of typical primary aldosteronism or Cushing syndrome, such as hypertension, hypokalemia, abnormal glucose metabolism. Laboratory tests indicated ARR> 3.7, ACTH <1.6 pg/mL, and a postoperative pathological diagnosis was adrenal cortical adenoma. Subclinical coexistence of both diseases was presented in this case. This type is not fully recognized in current guidelines and reports, and deserves more detailed discussion.

Keywords

• |adrenal incidentaloma|subclinical primary aldosteronism|subclinical cushing syndrome