Ожирение и метаболизм (Jun 2008)
Effect of thiazolidinediones on insulin resistance and cardiovascular risk factors
Abstract
The development of new, more effective ways of multivariate control of type 2 diabetes is currently the most important problem of endocrinology. This is caused by a high prevalence of this disease in the population, as well as a significant risk of complications leading to early morbidity and mortality of patients. Clinical management of patients with type 2 diabetes should be based on a thorough study of the mechanisms of this disease in order to correct the basic pathogenetic defects.