Nature Communications (Mar 2023)

Spatial transcriptomics using multiplexed deterministic barcoding in tissue

  • Johannes Wirth,
  • Nina Huber,
  • Kelvin Yin,
  • Sophie Brood,
  • Simon Chang,
  • Celia P. Martinez-Jimenez,
  • Matthias Meier

DOI
https://doi.org/10.1038/s41467-023-37111-w
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 15

Abstract

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Examining the spatially resolved transcriptome of tissue sections promises advances in biomedical research. Here, the authors present xDBiT, a versatile, microfluidics-based approach to cost-effectively measure the spatial transcriptome of multiple tissue sections in parallel.