Biomolecular Concepts (May 2020)

Polymorphism of MMP1 and MMP3 promoter regions and HR-HPV infection in women from Burkina Faso and Côte d‘Ivoire

  • Prosper Bado,
  • Florencia Djigma Wendkuuni,
  • Mahoukèdè Zohoncon Théodora,
  • Dorcas Obiri-Yeboah,
  • Alima Traoré Esther Mah,
  • Karim Ouattara Abdoul,
  • Clarisse Ouedraogo Teega-Wendé,
  • Toyin Bello Shoukrat Ohuwa,
  • Ayaovi Setor Marius,
  • Angèle Traore Ina Marie,
  • Apollinaire Horo,
  • Privat Kouakou Kouame,
  • Théophane Yonli Albert,
  • Charlemagne Ouedraogo,
  • Jacques Simpore

DOI
https://doi.org/10.1515/bmc-2020-0010
Journal volume & issue
Vol. 11, no. 1
pp. 116 – 124

Abstract

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The single nucleotide polymorphism (SNP) of the promoter region of MMP-1 (at 1607 bp) and MMP-3 (at 1171 bp) create Ets binding sites. Correlations between these SNPs and sensitivity to several biological processes such as metastasis and recurrence of cancer have been reported in several studies.

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