Histopathological dimensions differ between aganglionic and ganglionic bowel wall in children with Hirschsprung’s disease

Abstract

Highlights • To confirm ganglionic bowel wall in Hirschsprung’s disease, intra-operative frozen biopsy samples are required. This means a prolonged anesthesia time and a more immediate diagnostic method is warranted. • Muscle layers’ thicknesses differ between aganglionic and ganglionic bowel walls in children with Hirshsprung’s disease. These findings could be transferred to instant imaging techniques. • See the attached Supplementary Figure 2

Keywords

• Hirchsprung’s disease
• Bowel wall
• Histopathology
• Aganglionosis
• Ganglionosis
• Children