Nature Communications (Nov 2019)

Interplay between α2-chimaerin and Rac1 activity determines dynamic maintenance of long-term memory

  • Li Lv,
  • Yunlong Liu,
  • Jianxin Xie,
  • Yan Wu,
  • Jianjian Zhao,
  • Qian Li,
  • Yi Zhong

DOI
https://doi.org/10.1038/s41467-019-13236-9
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 12

Abstract

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Memory consolidation theory suggests that memory is maintained at a stable strength after formation. The authors show that memory is dynamically maintained at an intermediate level allowing a bidirectional regulation which is mediated by a balance between activated Rac1 and expressed α2-chimaerin.