Nature Communications (Jan 2020)

Highly durable crack sensor integrated with silicone rubber cantilever for measuring cardiac contractility

  • Dong-Su Kim,
  • Yong Whan Choi,
  • Arunkumar Shanmugasundaram,
  • Yun-Jin Jeong,
  • Jongsung Park,
  • Nomin-Erdene Oyunbaatar,
  • Eung-Sam Kim,
  • Mansoo Choi,
  • Dong-Weon Lee

DOI
https://doi.org/10.1038/s41467-019-14019-y
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 13

Abstract

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Measuring cardiac contractility is challenging. Here, the authors encapsulated a crack-based sensor with polydimethylsiloxane, thereby endowing the sensor with the stability to measure cardiac contractility for up to 26 days as well as monitoring drug-induced cardiac toxicity in cell culture.