精准医学杂志 (Oct 2023)

EFFICACY AND SAFETY OF COLD SNARE POLYPECTOMY IN TREATMENT OF COLORECTAL POLYPS WITH A DIAMETER OF 10-15 mm

  • YANG Guili, QIU Yuanzhe, SONG Mingquan, SUN Xueguo, LI Qian, LIU Fuguo

DOI
https://doi.org/10.13362/j.jpmed.202305011
Journal volume & issue
Vol. 38, no. 5
pp. 423 – 426

Abstract

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Objective To investigate the safety and efficacy of cold snare polypectomy (CSP) versus hot snare polypectomy (HSP) in the treatment of colorectal polyps with a diameter of 10-15 mm. Methods A total of 138 patients who underwent colonoscopy and planned to undergo polypectomy (at least one colorectal polyp with a maximum diameter of 10-15 mm) in Department of Gastroenterology, Laoshan Branch of The Affiliated Hospital of Qingdao University, from June 2022 to February 2023 were randomly divided into CSP group with 76 patients and HSP group with 62 patients. The two groups were compared in terms of the efficacy of polypectomy (complete resection rate and en bloc resection rate) and safety indicators (proportion of patients with intraoperative bleeding, delayed bleeding, intraoperative perforation, delayed perforation, and postoperative reactive serocolitis). Results The HSP had a complete resection rate of 98.4% and an en bloc resection rate of 96.8%, while the CSP group had a complete resection rate of 97.3% and an en bloc resection rate of 98.7%; there were no significant differences in the above efficacy indicators between the two groups (P>0.05). In the CSP group, 2 patients experienced intraoperative bleeding, while there were no patients with delayed bleeding, intraoperative and delayed perforation, or reactive serocolitis, and a total of 82 titanium clips were used in 71 patients; in the HSP group, 1 patient experienced intraoperative bleeding, 2 patients experienced delayed bleeding, and 4 patients developed reactive serocolitis, while there were no patients with intraoperative and delayed perforation, and a total of 72 titanium clips were used in 61 patients. There were no significant differences in the above safety indicators between the two groups (P>0.05). Conclusion CSP is safe and effective in removing colorectal polyps with a diameter of 10-15 mm and is thus re-commended for clinical application.

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