Toward a Phage Cocktail for Tuberculosis: Susceptibility and Tuberculocidal Action of Mycobacteriophages against Diverse Mycobacterium tuberculosis Strains

Carlos A. Guerrero-Bustamante; Rebekah M. Dedrick; Rebecca A. Garlena; Daniel A. Russell; Graham F. Hatfull

doi:10.1128/mBio.00973-21

mBio (Jun 2021)

Toward a Phage Cocktail for Tuberculosis: Susceptibility and Tuberculocidal Action of Mycobacteriophages against Diverse Mycobacterium tuberculosis Strains

Carlos A. Guerrero-Bustamante,
Rebekah M. Dedrick,
Rebecca A. Garlena,
Daniel A. Russell,
Graham F. Hatfull

Affiliations

Carlos A. Guerrero-Bustamante: ORCiD; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Rebekah M. Dedrick: ORCiD; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Rebecca A. Garlena: Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Daniel A. Russell: ORCiD; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Graham F. Hatfull: ORCiD; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

DOI: https://doi.org/10.1128/mBio.00973-21
Journal volume & issue: Vol. 12, no. 3

Abstract

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Tuberculosis kills 1.5 million people each year, and resistance to commonly used antibiotics contributes to treatment failures. The therapeutic potential of bacteriophages against Mycobacterium tuberculosis

Published in mBio

ISSN: 2161-2129 (Print); 2150-7511 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/mbio

About the journal