Medical Review (Oct 2024)

Understanding autoimmune response after SARS-CoV-2 infection and the pathogenesis/mechanisms of long COVID

  • Guo Ming,
  • Shang Shunlai,
  • Li Mengfei,
  • Cai Guangyan,
  • Li Ping,
  • Chen Xiangmei,
  • Li Qinggang

DOI
https://doi.org/10.1515/mr-2024-0013
Journal volume & issue
Vol. 4, no. 5
pp. 367 – 383

Abstract

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COVID-19 posed a major challenge to the healthcare system and resources worldwide. The popularization of vaccines and the adoption of numerous prevention and control measures enabled the gradual end of the COVID-19 pandemic. However, successive occurrence of autoimmune diseases in patients with COVID-19 cannot be overlooked. Long COVID has been the major focus of research due to the long duration of different symptoms and the variety of systems involved. Autoimmunity may play a crucial role in the pathogenesis of long COVID. Here, we reviewed several autoimmune disorders occurring after COVID-19 infection and the pathogenesis of long COVID.

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