A Short Report. Large Solitary Distant Metastasis of Cutaneous Squamous Cell Carcinoma to Skin Graft Site with Complete Response Following Definitive Radiotherapy

Abstract

Metastases of cutaneous squamous cell carcinoma (cSCC) in surgical sites distant from the primary lesion is anecdotally regarded as common but seldom reported. Patients with this condition usually have surgical treatment of the metastasis. The presented case is a 77-year-old immunocompetent male. He had surgery for a scalp primary cSCC that was closed with a split thickness skin graft (SSG). He developed a four centimetre (cm) solitary symptomatic metastatic cSCC in the SSG donor site on the right thigh 3 months after graft harvesting. There was a complete response of this metastasis following definitive curative radiotherapy until death from further metastatic disease six months later. Radiotherapy can be an alternative to surgery for large cSCC metastasis.

Keywords

• Skin neoplasms
• Skin transplantation
• Neoplasm metastasis
• Radiotherapy