Cutaneous toxicities from targeted therapies used in oncology: Literature review of clinical presentation and management

Abstract

With the development of molecular targeted therapies, a wide array of dermatologic toxicities is appearing. Their prevention, recognition, and management by dermatologists is critical to ensure antineoplastic treatment continuation. The objective of this study was to provide a literature review of the most common dermatologic toxicities due to targeted therapies in oncologic patients, including their clinical presentation, prevention, and management.

Keywords

• Molecular targeted therapies
• antineoplastic agents
• drug-related side effects and adverse events
• dermatological toxicities
• supportive care