Кубанский научный медицинский вестник (Jun 2015)

COMPARES THE TWO MODELS OF EXPERIMENTAL CARDIOPATIC AMYLOIDOSIS

  • N. V. Sokolovsky,
  • V. B. Brin,
  • K. M. Kozyrev,
  • O. T. Kabisov

Journal volume & issue
no. 3
pp. 101 – 105

Abstract

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To study the experimental system cardiopatic amyloidosis authors were first obtained by the model in aged rats that allows us to study the etiology and pathogenesis of this disease, and to develop methods of prevention and treatment. Comparative analysis of functional and morphological changes led to the conclusion that in order to further study cardiopatic amyloidosis is advisable to apply a technique with the addition of homogenate of rat myocardium, as in this case, alterative changes in the heart are most pronounced, with minimal changes in other organs and tissues.

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