Immune mechanisms of community-acquired pneumonia and copd due to infectious etiology and methods of immunotherapy

Abstract

Novadays a growing number of immunodependent diseases observed. There are 3 main groups of diseases of the immune system: immunodeficiency, allergic and autoimmune diseases. Also at the foundation of the brocken functions of the immune system could be the age of the patients, the chronic diseases, the localization of the inflammatory process, etiological characterization of the pathogen and various disorders of the immune system, especially in the case of existing genetic defects. In recent years, the increasing significance of conditionally pathogenic microflora in the development of pathology associated with the infection. Community-acquired pneumonia and chronic obstructive pulmonary disease (COPD) are characterized by high morbidity and mortality. The inclusion in the traditional therapy drugs with immunomodulatory effects helps enhance the action the treatment. Azoximer bromide could helps to reduce the duration and severity of the disease and reduce the incidence of severe forms of the disease. Also in recent years, the immunomodulatory drugs are of special interest immunomodulators of bacterial origin on the basis of which are constructed of antibacterial therapeutic vaccine. All of the above indicates the need to further develop pathogenetic, including immunocorrecting therapy, especially in severe disease.

Keywords

• community-acquired pneumonia
• copd
• adaptive immunity
• innate immunity
• immunotherapy
• immunomodulators
• antimicrobial therapeutic vaccines