Sleep Science
(Dec 2023)
Effects of 3D Airway Geometry on the Airflow of Adults with Cleft Lip and Palate and Obstructive Sleep Apnea: A Functional Imaging Study
Leticia Dominguez Campos,
Inge Elly Kiemle Trindade,
Sergio Henrique Kiemle Trindade,
Luiz André Freire Pimenta,
Julia Kimbell,
Amelia Drake,
Maria Noel Marzano-Rodrigues,
Ivy Kiemle Trindade-Suedam
Affiliations
Leticia Dominguez Campos
Laboratory of Physiology, Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, Bauru, SP, Brazil
Inge Elly Kiemle Trindade
Laboratory of Physiology, Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, Bauru, SP, Brazil
Sergio Henrique Kiemle Trindade
ORCiD
Laboratory of Physiology, Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, Bauru, SP, Brazil
Luiz André Freire Pimenta
Department of Biological Sciences, School of Dentistry, Universidade de São Paulo, Bauru, SP, Brazil
Julia Kimbell
School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America
Amelia Drake
School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America
Maria Noel Marzano-Rodrigues
Laboratory of Physiology, Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, Bauru, SP, Brazil
Ivy Kiemle Trindade-Suedam
Laboratory of Physiology, Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, Bauru, SP, Brazil
DOI
https://doi.org/10.1055/s-0043-1776868
Journal volume & issue
Vol. 16,
no. 04
pp.
e430
– e438
Abstract
Read online
Objective Individuals with cleft lip and palate (CLP) are at a high risk of developing obstructive sleep apnea (OSA). Hypothetically, the severity of OSA might be associated with the morphology of the upper airway (UAW) and the characteristics of the airflow. Thus, the present study aimed to assess and compare, in adults with CLP and skeletal class-III discrepancy, with or without OSA, simulations of airflow resistance and pressure according to the geometrical characteristics of the UAW and cephalometric parameters.
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