Light controlled biomaterials for regulating cell migration and differentiation

Changhao Tian; Junsheng Zhang; Jie Gu; Wenfei Li; Yi Cao

Smart Materials in Medicine (Jan 2022)

Light controlled biomaterials for regulating cell migration and differentiation

Changhao Tian,
Junsheng Zhang,
Jie Gu,
Wenfei Li,
Yi Cao

Affiliations

Changhao Tian: School of Ophthalmology & Optometry, School of Biomedical Engineering, Wenzhou Medical, University, Wenzhou, Zhejiang, 325035, China; Collaborative Innovation Center of Advanced Microstructures, Key Laboratory of Intelligent Optical Sensing and Manipulation, National Laboratory of Solid State Microstructure, Department of Physics, Nanjing University, Nanjing, 210093, China
Junsheng Zhang: Collaborative Innovation Center of Advanced Microstructures, Key Laboratory of Intelligent Optical Sensing and Manipulation, National Laboratory of Solid State Microstructure, Department of Physics, Nanjing University, Nanjing, 210093, China
Jie Gu: Collaborative Innovation Center of Advanced Microstructures, Key Laboratory of Intelligent Optical Sensing and Manipulation, National Laboratory of Solid State Microstructure, Department of Physics, Nanjing University, Nanjing, 210093, China
Wenfei Li: School of Ophthalmology & Optometry, School of Biomedical Engineering, Wenzhou Medical, University, Wenzhou, Zhejiang, 325035, China; Collaborative Innovation Center of Advanced Microstructures, Key Laboratory of Intelligent Optical Sensing and Manipulation, National Laboratory of Solid State Microstructure, Department of Physics, Nanjing University, Nanjing, 210093, China; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, Institute, University of Chinese Academy of Sciences, Wenzhou, 325001, China
Yi Cao: School of Ophthalmology & Optometry, School of Biomedical Engineering, Wenzhou Medical, University, Wenzhou, Zhejiang, 325035, China; Collaborative Innovation Center of Advanced Microstructures, Key Laboratory of Intelligent Optical Sensing and Manipulation, National Laboratory of Solid State Microstructure, Department of Physics, Nanjing University, Nanjing, 210093, China; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, Institute, University of Chinese Academy of Sciences, Wenzhou, 325001, China; Corresponding author. School of Ophthalmology & Optometry, School of Biomedical Engineering, Wenzhou Medical, University, Wenzhou, Zhejiang, 325035, China.

Journal volume & issue: Vol. 3
pp. 209 – 216

Abstract

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Cell microenvironments in human body are always complex, dynamic, and asymmetric. Light-controlled materials can mimic different physical and chemical environments non-invasively, in site, and dynamically, as a result, is attracting increasing attention in tissue engineering, cancer biology, and regenerating medicine. In this review, we discuss different light-controlled materials regulating cell behaviors. By controlling mechanical or cell adhesion properties, these materials synthesized by functional proteins or light-sensitive chemical groups can mimic microenvironments and regulate cell behaviors like migration and differentiation.

Published in Smart Materials in Medicine

ISSN: 2590-1834 (Online)
Publisher: KeAi Communications Co., Ltd.
Country of publisher: China
LCC subjects: Technology
Website: https://www.keaipublishing.com/en/journals/smart-materials-in-medicine/

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