SARS-CoV-2 RNA detection in cerebrospinal fluid: Presentation of two cases and review of literature

Abstract

Neurological manifestations of SARS-CoV-2 infection are multiple and heterogeneous. However, confirmation of nervous system impairment by viral RNA detection in cerebrospinal fluid (CSF) is uncommon. We report two cases of central nervous system (CNS) involvement with positive real-time reverse-transcriptase polymerase chain reaction (RT-PCR) test in CSF.

Keywords

• SARS-CoV-2
• SARS-CoV-2 neurological manifestations
• SARS-CoV-2 infection
• Meningoencephalitis
• Encephalitis
• Myelitis