Ologen collagen matrix for bleb repair in long standing sweating bleb- A case report with histopathological correlation

Abstract

A 68-year-old man, presented with reduced vision and hypotony 6 years after combined cataract + glaucoma (phacoemulsification + trabeculectomy + intraocular lens) surgery with Mitomycin-C, clinical evaluation depicted a sweating bleb. Surgical repair was done with the use of donor scleral patch graft and collagen matrix implant along with conjunctival advancement. Histopathology of the excised thinned-out bleb wall showed a single layer of metaplastic conjunctival epithelium with the complete absence of goblet cells. The use of adjuvant mitomycin-C in trabeculectomy is known to cause bleb leak and associated complications in the long run. However, the histopathological features of sweating blebs and their surgical management is not well defined in the literature.

Keywords

• collagen matrix
• metaplasia
• mitomycin c
• sweating blebs