Isostreptazolin and Sannaphenol, Two New Metabolites from Streptomyces sannanensis

Abstract

Two new compounds, isostreptazolin (1) and sannaphenol (2), were isolated from the culture broth of Streptomyces sannanensis and their structures elucidated on the basis of 1D and 2D NMR as well as MS, IR and UV spectroscopic data analysis. The cytotoxic activity of 1 and 2 were evaluated. Both compounds were inactive against H460 and HeLa cell lines at 100 mM.

Keywords

• isostreptazolin
• sannaphenol
• Streptomyces sannanensis