Communications Biology (Feb 2021)
A novel canine reference genome resolves genomic architecture and uncovers transcript complexity
- Chao Wang,
- Ola Wallerman,
- Maja-Louise Arendt,
- Elisabeth Sundström,
- Åsa Karlsson,
- Jessika Nordin,
- Suvi Mäkeläinen,
- Gerli Rosengren Pielberg,
- Jeanette Hanson,
- Åsa Ohlsson,
- Sara Saellström,
- Henrik Rönnberg,
- Ingrid Ljungvall,
- Jens Häggström,
- Tomas F. Bergström,
- Åke Hedhammar,
- Jennifer R. S. Meadows,
- Kerstin Lindblad-Toh
Affiliations
- Chao Wang
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- Ola Wallerman
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- Maja-Louise Arendt
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- Elisabeth Sundström
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- Åsa Karlsson
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- Jessika Nordin
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- Suvi Mäkeläinen
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- Gerli Rosengren Pielberg
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- Jeanette Hanson
- Department of Clinical Sciences, Swedish University of Agricultural Sciences
- Åsa Ohlsson
- Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences
- Sara Saellström
- Department of Clinical Sciences, Swedish University of Agricultural Sciences
- Henrik Rönnberg
- Department of Clinical Sciences, Swedish University of Agricultural Sciences
- Ingrid Ljungvall
- Department of Clinical Sciences, Swedish University of Agricultural Sciences
- Jens Häggström
- Department of Clinical Sciences, Swedish University of Agricultural Sciences
- Tomas F. Bergström
- Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences
- Åke Hedhammar
- Department of Clinical Sciences, Swedish University of Agricultural Sciences
- Jennifer R. S. Meadows
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- Kerstin Lindblad-Toh
- Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University
- DOI
- https://doi.org/10.1038/s42003-021-01698-x
- Journal volume & issue
-
Vol. 4,
no. 1
pp. 1 – 11
Abstract
Here, the authors report an improved de novo reference genome for the domestic dog based on a female German Shepherd named Mischka. The new genome increases contiguity 55-fold over the previous dog assembly and uncovers functional elements that were not previously identifiable.
