Cobalt-catalyzed branched selective hydroallylation of terminal alkynes

Abstract

Selectively generating “skipped” dienes, where two carbon–carbon double bonds are separated by a saturated carbon center, is an interesting problem in organic chemistry, with few reliable, catalytic methods currently available. Here, the authors report branched selective hydroallylation of terminal alkynes with allylic bromides to form skipped dienes, via cobalt catalysis.