IJU Case Reports (Jan 2024)

A case of condyloma acuminatum of the bladder concurrently diagnosed with urothelial carcinoma

  • Ibuki Tsuru,
  • Masaki Nakamura,
  • Taro Izumi,
  • Akihiro Ono,
  • Sakiko Miura,
  • Teppei Morikawa,
  • Kazuyoshi Shigehara,
  • Tadaichi Kitamura,
  • Haruki Kume,
  • Yoshiyuki Shiga

DOI
https://doi.org/10.1002/iju5.12664
Journal volume & issue
Vol. 7, no. 1
pp. 42 – 45

Abstract

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Introduction Condyloma acuminatum usually occurs in the external genitalia and rarely in the bladder mucosa. Here, we report a case of condyloma acuminatum of the bladder that was detected concurrently with urothelial carcinoma. Case presentation A 42‐year‐old man was referred to our urology department with positive urine cytology for urothelial carcinoma. Cystoscopy revealed a broad‐base nonpapillary bladder tumor. The patient underwent a transurethral resection of the bladder tumor. Pathological examination revealed urothelial carcinoma, high‐grade pT1, and concurrent resection of condyloma acuminatum. DNA was extracted from the paraffin‐embedded transurethral resection of the bladder tumor tissue specimens. HPV11 was detected in condylomas by PCR and in situ hybridization, whereas HPV was not detected in urothelial carcinomas. Conclusion We report a rare case of condyloma acuminatum of the bladder that was concurrently diagnosed with urothelial carcinoma from the same site.

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