Nature Communications (Nov 2016)

Structure of the ribosome post-recycling complex probed by chemical cross-linking and mass spectrometry

  • Kristin Kiosze-Becker,
  • Alessandro Ori,
  • Milan Gerovac,
  • André Heuer,
  • Elina Nürenberg-Goloub,
  • Umar Jan Rashid,
  • Thomas Becker,
  • Roland Beckmann,
  • Martin Beck,
  • Robert Tampé

DOI
https://doi.org/10.1038/ncomms13248
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 9

Abstract

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Ribosome recycling orchestrated by ABCE1 connects translation termination and mRNA surveillance mechanisms with re-initiation. Using a cross-linking and mass spectrometry approach, Kiosze-Becker et al. provide new information on the large conformational rearrangements that occur during ribosome recycling.