Optimal scan time for evaluation of parathyroid adenoma with [18F]-fluorocholine PET/CT

Abstract

Background. Parathyroid adenomas, the most common cause of primary hyperparathyroidism, are benign tumours which autonomously produce and secrete parathyroid hormone. [18F]-fluorocholine (FCH), PET marker of cellular proliferation, was recently demonstrated to accumulate in lesions representing enlarged parathyroid tissue; however, the optimal time to perform FCH PET/CT after FCH administration is not known. The aim of this study was to determine the optimal scan time of FCH PET/CT in patients with primary hyperparathyroidism.

Keywords

• [18f]-fluorocholine pet/ct
• lesions representing enlarged parathyroid tissue
• triple-phase
• standardized up-take value
• retention index
• lesion contrast