Large-scale computational discovery and analysis of virus-derived microbial nanocompartments

Michael P. Andreas; Tobias W. Giessen

doi:10.1038/s41467-021-25071-y

Nature Communications (Aug 2021)

Large-scale computational discovery and analysis of virus-derived microbial nanocompartments

Michael P. Andreas,
Tobias W. Giessen

Affiliations

Michael P. Andreas: Department of Biomedical Engineering, University of Michigan Medical School
Tobias W. Giessen: Department of Biomedical Engineering, University of Michigan Medical School

DOI: https://doi.org/10.1038/s41467-021-25071-y
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 16

Abstract

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Encapsulins are microbial protein compartments that sequester specific enzymes and are formed by self-assembly of a viral-like capsid protein. Here, Andreas and Giessen carry out a large-scale computational analysis of prokaryotic genomes to present a curated set of over 6,000 encapsulin-like systems, and present hypotheses about their potential biological functions.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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