Natural Products and Bioprospecting (Feb 2022)

Three new pyrrole alkaloids from the endophytic fungus Albifimbria viridis

  • Pan-Pan Wei,
  • Jia-Cheng Ji,
  • Xu-Jun Ma,
  • Zheng-Hui Li,
  • Hong-Lian Ai,
  • Xin-Xiang Lei,
  • Ji-Kai Liu

Journal volume & issue
Vol. 12, no. 1
pp. 1 – 5


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Abstract Three new pyrrole alkaloids albifipyrrols A–C (1–3), were isolated from the endophytic fungus Albifimbria viridis collected from the Chinese medicinal plant. Their structures were elucidated by extensive NMR and HRESIMS spectrometric analyses. All compounds were evaluated for immunosuppressive activity. Fortunately, compound 2 exhibits certain inhibition specifically against the LPS-induced proliferation of B lymphocyte cells with IC50 value 16.16 μM. Graphical Abstract