Nature Communications (Nov 2021)
Photo-induced copper-catalyzed sequential 1,n-HAT enabling the formation of cyclobutanols
Abstract
Cyclobutanols are difficult structures to access given their inherent ring strain. Here, the authors present a method to form substituted cyclobutanols from a photocatalytic cascade reaction, proceeding via a 1,5- or 1,6-hydrogen atom transfer and subsequent ring closure.