CUTting through the distance: A disease-relevant long-range ONECUT1 enhancer
Anthony S. Wokasch,
Maureen Gannon
Affiliations
Anthony S. Wokasch
Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA
Maureen Gannon
Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA; Department of Veterans Affairs Tennessee Valley, Nashville, TN, USA; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA; Corresponding author
In two recent issues of Cell Reports, Kaplan et al.1 and Merz et al.2 identify a distal enhancer region within the OC1 gene and demonstrate its relevance to OC1 expression, pancreatic endocrine differentiation, and diabetes susceptibility.
