Diagnostic accuracy of (1→3)-β-D-glucan to predict Pneumocystis jirovecii pneumonia in non-HIV-infected patients

Abstract

Pneumocystis jirovecii pneumonia (PCP) is a common and potentially fatal opportunistic infection in immunocompromised non-HIV individuals. There are problems with clinical and diagnostic protocols for PCP that lack sensitivity and specificity. We designed a retrospective study to compared several methods that were used in diagnostics of PCP.

Keywords

• pneumocystis jirovecii pneumonia
• (1→3)-β-d-glucan
• dif
• real-time pcr
• colonization with p. jirovecii
• non-hiv-infected patients