Department of Medicine, National University Health System, Singapore
Benjamin Yong-Qiang Tan
Division of Neurology, Department of Medicine, National University Health System, Singapore; and Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore,Singapore
Sai-Meng Tham
Department of Medicine, National University Health System, Singapore
Celine Yan-Shan Tan
Department of Medicine, National University Health System, Singapore
Mingxue Jing
Division of Neurology, Department of Medicine, National University Health System, Singapore
Renarebecca Sagayanathan
Division of Neurology, Department of Medicine, National University Health System, Singapore
Jin Tao Chen
Division of Neurology, Department of Medicine, National University Health System, Singapore
Lily Y. H. Wong
Division of Neurology, Department of Medicine, National University Health System, Singapore
Aftab Ahmad
Department of Neurology, Ng Teng Fong General Hospital, Singapore
Faheem Ahmed Khan
Department of Intensive Care Medicine, Ng Teng Fong General Hospital, Singapore
Maznah Marmin
Department of Neurology, Ng Teng Fong General Hospital, Singapore
Fadhlina Binte Hassan
Department of Neurology, Ng Teng Fong General Hospital, Singapore
Attikon University Hospital, National and Kapodistrian University of Athens, Greece
Dimitra Dimopoulou
Attikon University Hospital, National and Kapodistrian University of Athens, Greece
Arvind K. Sharma
Zydus Hospital, India
Kenam Shah
Zydus Hospital, India
Bhargesh Patel
Zydus Hospital, India
Suktara Sharma
GCS Medical College, India
R. N. Komalkumar
Yashoda Hospital, India
R. V. Meenakshi
Senthil Multi Specialty Hospital, India
Shikha Talati
Department of Psychiatry, Geetanjali Medical College and Hospital, India
Hock Luen Teoh
Division of Neurology, Department of Medicine, National University Health System, Singapore; and Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Cyrus S. Ho
Department of Psychological Medicine, National University of Singapore, Singapore
Roger C. Ho
Department of Psychological Medicine and Institute of Health Innovation and Technology (iHealthtech), National University of Singapore, Singapore
Vijay K. Sharma
Division of Neurology, Department of Medicine, National University Health System, Singapore; and Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
BackgroundThe coronavirus disease 2019 (COVID-19) pandemic has led to significant strain on front-line healthcare workers.AimsIn this multicentre study, we compared the psychological outcomes during the COVID-19 pandemic in various countries in the Asia-Pacific region and identified factors associated with adverse psychological outcomes.MethodFrom 29 April to 4 June 2020, the study recruited healthcare workers from major healthcare institutions in five countries in the Asia-Pacific region. A self-administrated survey that collected information on prior medical conditions, presence of symptoms, and scores on the Depression Anxiety Stress Scales and the Impact of Events Scale-Revised were used. The prevalence of depression, anxiety, stress and post-traumatic stress disorder (PTSD) relating to COVID-19 was compared, and multivariable logistic regression identified independent factors associated with adverse psychological outcomes within each country.ResultsA total of 1146 participants from India, Indonesia, Singapore, Malaysia and Vietnam were studied. Despite having the lowest volume of cases, Vietnam displayed the highest prevalence of PTSD. In contrast, Singapore reported the highest case volume, but had a lower prevalence of depression and anxiety. In the multivariable analysis, we found that non-medically trained personnel, the presence of physical symptoms and presence of prior medical conditions were independent predictors across the participating countries.ConclusionsThis study highlights that the varied prevalence of psychological adversity among healthcare workers is independent of the burden of COVID-19 cases within each country. Early psychological interventions may be beneficial for the vulnerable groups of healthcare workers with presence of physical symptoms, prior medical conditions and those who are not medically trained.