Acta Veterinaria (Sep 2017)

IGF1 Gene Polymorphism in Selected Species of the Canidae Family

  • Jakubczak Andrzej,
  • Gryzinska Magdalena,
  • Horecka Beata,
  • Jezewska-Witkowska Grazyna

DOI
https://doi.org/10.1515/acve-2017-0034
Journal volume & issue
Vol. 67, no. 3
pp. 426 – 431

Abstract

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The gene IGF1 has been shown to have a significant influence on the size of individuals, including animals of the Canidae family. In this study we determined SNP mutations of the IGF1 gene in dogs, raccoon dogs and farmed and free-living red foxes from Poland and Canada. No SNP mutations were noted in dogs or raccoon dogs, but a total of 14 single nucleotide polymorphisms were identified in foxes, including 12 substitutions, as well as one new mutation missense variant (exon 6) in wild Polish foxes and one synonymous mutation variant in wild foxes from Canada. We identified specific SNP profiles characteristic only for farmed foxes and only for wild foxes, as well as specific SNP profiles or wild foxes from North America (Canada) and from Europe (Poland).

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