813 Combination of HexaBody-CD27 with PD-(L)1 blockade potentiates single-agent activity leading to enhanced human T-cell effector functions in vitro

• Jordan Blum,
• Alexander Muik,
• Isil Altintas,
• Friederike Gieseke,
• Aras Toker,
• Esther Breij,
• Tahamtan Ahmadi,
• Ugur Sahin,
• Kristel Kemper,
• Oezlem Tuereci,
• Kristina Nuermberger,
• Sina Fellermeier-Kopf,
• Andrea Imle,
• Anna-Lena Krause,
• Lidia Daszkiewicz

Affiliations

Jordan Blum

3Genmab, Plainsboro, NJ, USA

Alexander Muik

1BioNTech SE, Mainz, Germany

Isil Altintas

2Genmab, Utrecht, Netherlands

Friederike Gieseke

1BioNTech SE, Mainz, Germany

Aras Toker

1BioNTech SE, Mainz, Germany

Esther Breij

2Genmab, Utrecht, Netherlands

Tahamtan Ahmadi

3Genmab, Plainsboro, NJ, USA

Ugur Sahin

1BioNTech SE, Mainz, Germany

Kristel Kemper

2Genmab, Utrecht, Netherlands

Oezlem Tuereci

1BioNTech SE, Mainz, Germany

Kristina Nuermberger

1BioNTech SE, Mainz, Germany

Sina Fellermeier-Kopf

1BioNTech SE, Mainz, Germany

Andrea Imle

1BioNTech SE, Mainz, Germany

Anna-Lena Krause

1BioNTech SE, Mainz, Germany

Lidia Daszkiewicz

2Genmab, Utrecht, Netherlands