Genome Biology (Oct 2023)

The Quartet Data Portal: integration of community-wide resources for multiomics quality control

  • Jingcheng Yang,
  • Yaqing Liu,
  • Jun Shang,
  • Qiaochu Chen,
  • Qingwang Chen,
  • Luyao Ren,
  • Naixin Zhang,
  • Ying Yu,
  • Zhihui Li,
  • Yueqiang Song,
  • Shengpeng Yang,
  • Andreas Scherer,
  • Weida Tong,
  • Huixiao Hong,
  • Wenming Xiao,
  • Leming Shi,
  • Yuanting Zheng

DOI
https://doi.org/10.1186/s13059-023-03091-9
Journal volume & issue
Vol. 24, no. 1
pp. 1 – 19

Abstract

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Abstract The Quartet Data Portal facilitates community access to well-characterized reference materials, reference datasets, and related resources established based on a family of four individuals with identical twins from the Quartet Project. Users can request DNA, RNA, protein, and metabolite reference materials, as well as datasets generated across omics, platforms, labs, protocols, and batches. Reproducible analysis tools allow for objective performance assessment of user-submitted data, while interactive visualization tools support rapid exploration of reference datasets. A closed-loop “distribution-collection-evaluation-integration” workflow enables updates and integration of community-contributed multiomics data. Ultimately, this portal helps promote the advancement of reference datasets and multiomics quality control.

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