Frontiers in Public Health (Aug 2022)

Long-term effects of COVID-19 in diabetic and non-diabetic patients

  • Ricardo Wesley Alberca,
  • Yasmim Álefe Leuzzi Ramos,
  • Nátalli Zanete Pereira,
  • Danielle Rosa Beserra,
  • Anna Cláudia Calvielli Castelo Branco,
  • Raquel Leão Orfali,
  • Valeria Aoki,
  • Alberto Jose da Silva Duarte,
  • Maria Notomi Sato

DOI
https://doi.org/10.3389/fpubh.2022.963834
Journal volume & issue
Vol. 10

Abstract

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The literature presents several reports of the impact of glycemic control and diabetes in the inflammatory and coagulatory response during coronavirus disease 2019 (COVID-19). Nevertheless, the long-term impact of the COVID-19 in diabetic patients is still to be explored. Therefore, we recruited 128 patients and performed a longitudinal analysis on COVID-19-associated biomarkers of patients with COVID-19, tree and 6 months after COVID-19 recovery and put into perspective the possible long-term complication generated after COVID-19. In our investigation, we failed to verify any long-term modification on inflammatory biomarkers, but detected an increase in the glycemia and glycated hemoglobin in patients without any pre-existing history or diagnosis of diabetes (non-diabetic patients). Although diabetic and non-diabetic patients presented elevated levels of glycated hemoglobin, the c-peptide test indicated a normal beta cell function in all patients.

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