A clinical case of hypothyroidism with impaired higher cortical functions and anuria

Abstract

Relevance. A clinical case of hypothyroidism presenting with an unusual combination of symptoms is presented. Possible mechanisms for the development of the present clinical manifestations are reviewed, and the relationship to other disciplines is discussed. Aim and Objectives. To describe a clinical case in order to sensitize physicians to the neurologic manifestations of somatic diseases. Materials and methods. The patient was examined upon admission to the hospital, dynamic observation, and medical history was analyzed. Results. The presence in the patient of disorders of consciousness and higher cortical functions in combination with anuria and pronounced static and dynamic ataxia can be fully explained by decompensation of hypothyroidism. Conclusions. The presented clinical case demonstrates multisystemic manifestations of hypothyroidism; the patient's symptoms could require the attention of urologists, nephrologists, neurologists, therapists, and endocrinologists. The subacute onset of symptoms is important.

Keywords

• hypothyroidism
• anuria
• ataxia
• disorder of higher cortical functions.