Nanomaterials
(Jan 2023)
Biocompatibility and Antimicrobial Activity of Electrospun Fibrous Materials Based on PHB and Modified with Hemin
Polina M. Tyubaeva,
Ivetta A. Varyan,
Elena D. Nikolskaya,
Mariia R. Mollaeva,
Nikita G. Yabbarov,
Maria B. Sokol,
Margarita V. Chirkina,
Anatoly A. Popov
Affiliations
Polina M. Tyubaeva
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina Street, 119334 Moscow, Russia
Ivetta A. Varyan
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina Street, 119334 Moscow, Russia
Elena D. Nikolskaya
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina Street, 119334 Moscow, Russia
Mariia R. Mollaeva
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina Street, 119334 Moscow, Russia
Nikita G. Yabbarov
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina Street, 119334 Moscow, Russia
Maria B. Sokol
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina Street, 119334 Moscow, Russia
Margarita V. Chirkina
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina Street, 119334 Moscow, Russia
Anatoly A. Popov
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina Street, 119334 Moscow, Russia
DOI
https://doi.org/10.3390/nano13020236
Journal volume & issue
Vol. 13,
no. 2
Abstract
Read online
The effect of the hemin (Hmi) on the structure and properties of nanocomposite electrospun materials based on poly-3-hydroxybutyrate (PHB) is discussed in the article. The additive significantly affected the morphology of fibers allowed to produce more elastic material and provided high antimicrobial activity. The article considers also the impact of the hemin on the biocompatibility of the nonwoven material based on PHB and the prospects for wound healing.
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