Communications Biology (Dec 2022)

Controlled release of growth factors using synthetic glycosaminoglycans in a modular macroporous scaffold for tissue regeneration

  • Z. Söderlund,
  • A. Ibáñez-Fonseca,
  • S. Hajizadeh,
  • J. C. Rodríguez-Cabello,
  • J. Liu,
  • L. Ye,
  • E. Tykesson,
  • L. Elowsson,
  • G. Westergren-Thorsson

DOI
https://doi.org/10.1038/s42003-022-04305-9
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 13

Abstract

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Functionalization of a macroporous elastic-like recombinamer hydrogel with synthetic glycosaminoglycans enables controlled binding and release of growth factors for blood vessel formation with reduced immune response in a subcutaneous mouse model.