Pharmacoeconomic analysis of treatment of children with acute lymphoblastic leukemia according to ALL-MB-2002 protocol

Abstract

Comparative pharmacoeconomic analysis of treatment according to ALL-MB-2002 protocol between two groups of children with acute lymphoblastic leukemia (ALL) (n=53) depending on use of intravenous immunoglobulin (IVIG) aiming to infectious complications preventing was conducted. It is shown, that actual protocol cost in group of children treating with IVIG in 1,5 times low (р<0,001). Price reduction of medicamentous treatment in this group of patients occur due to reduction of complications treatment cost, p<0,001. Decreasing time of treatment interruptions in group of patients with IVIG result in severe reduction of hospitalization cost (p<0,001). Application of this drug is more economic because of almost in 2 times reduction cost/efficiency ratio and 1,4 times increasing of additional years of life in ALL patients.

Keywords

• children
• acute lymphoblastic leukemia
• pharmacoeconomic analysis
• intravenous immunoglobulin