Success rate of undescended testicle treatment with human chorionic gonadotropin

Abstract

Introduction: Cryptorchidism is a disorder of the testicles, when during a physical exam, testicles, one or both of them, are not found in the scrotum, but are found either along the inguinal canal or in the abdomen. Two main modalities of treatment are hormonal and surgical treatment. Aim: The aim of this paper was to determine the success rate of hormonal therapy with human chorionic gonadotropin (hCG) in undescended testicle treatment in patients treated at the Institute for Child and Youth Health Care in Vojvodina, from January 1, 2010, to December 31, 2017. Material and methods: This research included the patients from the Institute for Child and Youth Health Care in Vojvodina ages 0-18, treated from January 1, 2010, to December 31, 2017. Medical documentation has been analyzed and interpreted using methods of descriptive statistic. The research included boys with undescended testicles, to whom the hormonal therapy was indicated. Patients were divided into 3 groups (6 years). The therapy was applied twice a week, in the course of 5 weeks (hCG 250-1000 IJ/dose). The position 12 months after therapy was used as a final position. Results: The hormonal descend was achieved in 63 patients (62.4%) of the total number of patients. Тhe highest success rate was achieved in oldest of our patients (80%). Conclusion: Hormonal therapy with hCG leads to descent in a high percentage, with very little transitory adverse effects, and it is an important modality in undescended testicles treatment.

Keywords

• hormonal therapy
• human chorionic gonadotropin
• cryptorchidism
• genital anomalies