FBXO45 levels regulated ferroptosis renal tubular epithelial cells in a model of diabetic nephropathy by PLK1

Zhu Bingming; Hu Yongxuan; Wu Ruishan; Yu Quan; Wen Wangrong

doi:10.1515/med-2024-0971

Open Medicine (May 2024)

FBXO45 levels regulated ferroptosis renal tubular epithelial cells in a model of diabetic nephropathy by PLK1

Zhu Bingming,
Hu Yongxuan,
Wu Ruishan,
Yu Quan,
Wen Wangrong

Affiliations

Zhu Bingming: Department of Clinical Laboratory, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China
Hu Yongxuan: Department of Dermatology and Venereology, The 3rd Affiliated Hospital of SouthernMedical University, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, Guangzhou, 510600, China
Wu Ruishan: NHC Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute (Guangdong Provincial Fertility Hospital), Guangzhou, 510600, China
Yu Quan: Medical Experimental Research Center, School of Medicine, Jinan University, Guangzhou, Guangdong, 510630, China
Wen Wangrong: Clinical Laboratory Center, The Affiliated Shunde Hospital Of Jinan University, Foshan, Guangdong, 528305, China

DOI: https://doi.org/10.1515/med-2024-0971
Journal volume & issue: Vol. 19, no. 1
pp. 2107 – 18

Abstract

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This research aims to investigate the role and underlying biological mechanism of FBXO45 in regulating ferroptosis of renal fibrocytes in a diabetic nephropathy (DN) model.

Published in Open Medicine

ISSN: 2391-5463 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine
Website: https://www.degruyter.com/journal/key/med/html

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Abstract

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