FBXO45 levels regulated ferroptosis renal tubular epithelial cells in a model of diabetic nephropathy by PLK1
Zhu Bingming,
Hu Yongxuan,
Wu Ruishan,
Yu Quan,
Wen Wangrong
Affiliations
Zhu Bingming
Department of Clinical Laboratory, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China
Hu Yongxuan
Department of Dermatology and Venereology, The 3rd Affiliated Hospital of SouthernMedical University, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, Guangzhou, 510600, China
Wu Ruishan
NHC Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute (Guangdong Provincial Fertility Hospital), Guangzhou, 510600, China
Yu Quan
Medical Experimental Research Center, School of Medicine, Jinan University, Guangzhou, Guangdong, 510630, China
Wen Wangrong
Clinical Laboratory Center, The Affiliated Shunde Hospital Of Jinan University, Foshan, Guangdong, 528305, China
This research aims to investigate the role and underlying biological mechanism of FBXO45 in regulating ferroptosis of renal fibrocytes in a diabetic nephropathy (DN) model.