Developmental Cognitive Neuroscience (Oct 2024)
The development and structure of the HEALthy Brain and Child Development (HBCD) Study EEG protocol
- Nathan A. Fox,
- Koraly Pérez-Edgar,
- Santiago Morales,
- Natalie H. Brito,
- Alana M. Campbell,
- James F. Cavanagh,
- Laurel Joy Gabard-Durnam,
- Caitlin M. Hudac,
- Alexandra P. Key,
- Linda J. Larson-Prior,
- Ernest V. Pedapati,
- Elizabeth S. Norton,
- Rachel Reetzke,
- Timothy P. Roberts,
- Tara M. Rutter,
- Lisa S. Scott,
- Lauren C. Shuffrey,
- Martín Antúnez,
- Maeve R. Boylan,
- Bailey M. Garner,
- Britley Learnard,
- Savannah McNair,
- Marco McSweeney,
- Maria Isabella Natale Castillo,
- Jessica Norris,
- Olufemi Shakuur Nyabingi,
- Nicolò Pini,
- Alena Quinn,
- Rachel Stosur,
- Enda Tan,
- Sonya V. Troller-Renfree,
- Lydia Yoder
Affiliations
- Nathan A. Fox
- Department of Human Development and Quantitative Methodology, The University of Maryland, College Park, USA; Corresponding author.
- Koraly Pérez-Edgar
- Department of Psychology, The Pennsylvania State University, USA
- Santiago Morales
- Department of Psychology, University of Southern California, USA
- Natalie H. Brito
- Department of Applied Psychology; New York University, USA
- Alana M. Campbell
- Department of Psychiatry, University of North Carolina at Chapel Hill, USA
- James F. Cavanagh
- Department of Psychology, University of New Mexico, USA
- Laurel Joy Gabard-Durnam
- Department of Psychology, Northeastern University, USA
- Caitlin M. Hudac
- Department of Psychology and Carolina Autism and Neurodevelopment Research Center, University of South Carolina, USA
- Alexandra P. Key
- Department of Pediatrics and Marcus Autism Center, Emory University School of Medicine, USA
- Linda J. Larson-Prior
- Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, USA
- Ernest V. Pedapati
- Division of Child and Adolescent Psychiatry, Cincinnati Children’s Hospital Medical Center, USA
- Elizabeth S. Norton
- Roxelyn and Richard Pepper, Department of Communication Sciences and Disorders, Department of Medical Social Sciences, and Institute for Innovations in Developmental Sciences, Northwestern University, USA
- Rachel Reetzke
- Center for Autism Services, Science and Innovation, Kennedy Krieger Institute, USA; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, USA
- Timothy P. Roberts
- Department of Radiology, Children’s Hospital of Philadelphia, USA
- Tara M. Rutter
- Department of Psychiatry, Oregon Health and Science University, USA
- Lisa S. Scott
- Department of Psychology, University of Florida, USA
- Lauren C. Shuffrey
- Department of Child and Adolescent Psychiatry, NYU Grossman School of Medicine, USA
- Martín Antúnez
- Department of Human Development and Quantitative Methodology, The University of Maryland, College Park, USA
- Maeve R. Boylan
- Department of Psychology, University of Florida, USA
- Bailey M. Garner
- Department of Psychology, University of Florida, USA
- Britley Learnard
- Department of Psychiatry, University of Vermont, USA
- Savannah McNair
- Department of Human Development and Quantitative Methodology, The University of Maryland, College Park, USA
- Marco McSweeney
- Department of Human Development and Quantitative Methodology, The University of Maryland, College Park, USA
- Maria Isabella Natale Castillo
- Division of Newborn Medicine, Boston Children’s Hospital, Harvard Medical School, USA
- Jessica Norris
- Department of Human Development and Quantitative Methodology, The University of Maryland, College Park, USA
- Olufemi Shakuur Nyabingi
- Department of Psychology, University of California, Davis, USA
- Nicolò Pini
- Department of Psychiatry, Columbia University Irving Medical Center; Division of Developmental Neuroscience, New York State Psychiatric Institute, USA
- Alena Quinn
- Department of Psychology, University of South Carolina, USA
- Rachel Stosur
- Department of Human Development and Quantitative Methodology, The University of Maryland, College Park, USA
- Enda Tan
- Department of Human Development and Quantitative Methodology, The University of Maryland, College Park, USA
- Sonya V. Troller-Renfree
- Department of Human Development, Teachers College, Columbia University, USA
- Lydia Yoder
- Department of Human Development and Quantitative Methodology, The University of Maryland, College Park, USA
- Journal volume & issue
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Vol. 69
p. 101447
Abstract
The HEALthy Brain and Child Development (HBCD) Study, a multi-site prospective longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. Electroencephalography (EEG) is one of two brain imaging modalities central to the HBCD Study. EEG records electrical signals from the scalp that reflect electrical brain activity. In addition, the EEG signal can be synchronized to the presentation of discrete stimuli (auditory or visual) to measure specific cognitive processes with excellent temporal precision (e.g., event-related potentials; ERPs). EEG is particularly helpful for the HBCD Study as it can be used with awake, alert infants, and can be acquired continuously across development. The current paper reviews the HBCD Study’s EEG/ERP protocol: (a) the selection and development of the tasks (Video Resting State, Visual Evoked Potential, Auditory Oddball, Face Processing); (b) the implementation of common cross-site acquisition parameters and hardware, site setup, training, and initial piloting; (c) the development of the preprocessing pipelines and creation of derivatives; and (d) the incorporation of equity and inclusion considerations. The paper also provides an overview of the functioning of the EEG Workgroup and the input from members across all steps of protocol development and piloting.
