mBio (Oct 2021)

<i>In Situ</i> Visualization of the pKM101-Encoded Type IV Secretion System Reveals a Highly Symmetric ATPase Energy Center

  • Pratick Khara,
  • Liqiang Song,
  • Peter J. Christie,
  • Bo Hu

DOI
https://doi.org/10.1128/mBio.02465-21
Journal volume & issue
Vol. 12, no. 5

Abstract

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Bacterial type IV secretion systems (T4SSs) play central roles in antibiotic resistance spread and virulence. By cryo-electron tomography (CryoET), we solved the structure of the plasmid pKM101-encoded T4SS in the native context of the bacterial cell envelope.