A definitive haplotype map of structural variations determined by microarray analysis of duplicated haploid genomes

Tomoko Tahira; Koji Yahara; Yoji Kukita; Koichiro Higasa; Kiyoko Kato; Norio Wake; Kenshi Hayashi

doi:10.1016/j.gdata.2014.04.006

Genomics Data (Dec 2014)

A definitive haplotype map of structural variations determined by microarray analysis of duplicated haploid genomes

Tomoko Tahira,
Koji Yahara,
Yoji Kukita,
Koichiro Higasa,
Kiyoko Kato,
Norio Wake,
Kenshi Hayashi

Affiliations

Tomoko Tahira: Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
Koji Yahara: Biostatistics Center, Kurume University, Kurume, Japan
Yoji Kukita: Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
Koichiro Higasa: Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
Kiyoko Kato: Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Norio Wake: Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Kenshi Hayashi: Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

DOI: https://doi.org/10.1016/j.gdata.2014.04.006
Journal volume & issue: Vol. 2, no. C
pp. 55 – 59

Abstract

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Complete hydatidiform moles (CHMs) are tissues carrying duplicated haploid genomes derived from single sperms, and detecting copy number variations (CNVs) in CHMs is assumed to be sensitive and straightforward methods. We genotyped 108 CHM genomes using Affymetrix SNP 6.0 (GEO#: GSE18642) and Illumina 1 M-duo (GEO#: GSE54948). After quality control, we obtained 84 definitive haplotype consisting of 1.7 million SNPs and 2339 CNV regions. The results are presented in the database of our web site (http://orca.gen.kyushu-u.ac.jp/cgi-bin/gbrowse/humanBuild37D4_1/).

Published in Genomics Data

ISSN: 2213-5960 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Science: Biology (General): Genetics
Website: http://www.journals.elsevier.com/genomics-data/

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