Caught in the act

Hermann-Josef Meyer; Michael Rape

doi:10.7554/eLife.01127

eLife (Aug 2013)

Caught in the act

Hermann-Josef Meyer,
Michael Rape

Affiliations

Hermann-Josef Meyer: Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States
Michael Rape: Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States

DOI: https://doi.org/10.7554/eLife.01127
Journal volume & issue: Vol. 2

Abstract

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The crystal structure of a HECT E3 enzyme has been captured as it transfers ubiquitin to a target protein, revealing the dramatic changes in shape that enable it to modify particular residues in its targets.

Published in eLife

ISSN: 2050-084X (Online)
Publisher: eLife Sciences Publications Ltd
Country of publisher: United Kingdom
LCC subjects: Medicine; Science: Biology (General)
Website: https://elifesciences.org

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Abstract

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