GigaByte (Nov 2021)
Genomic features of Mycobacterium avium subsp. hominissuis isolated from pigs in Japan
- Tetsuya Komatsu ,
- Kenji Ohya ,
- Atsushi Ota ,
- Yukiko Nishiuchi ,
- Hirokazu Yano ,
- Kayoko Matsuo ,
- Justice Opare Odoi ,
- Shota Suganuma ,
- Kotaro Sawai ,
- Akemi Hasebe ,
- Tetsuo Asai ,
- Tokuma Yanai ,
- Hideto Fukushi ,
- Takayuki Wada ,
- Shiomi Yoshida ,
- Toshihiro Ito ,
- Kentaro Arikawa ,
- Mikihiko Kawai ,
- Manabu Ato ,
- Anthony D Baughn ,
- Tomotada Iwamoto ,
- Fumito Maruyama
Affiliations
- Tetsuya Komatsu
- ORCiD
- Aichi Prefectural Chuo Livestock Hygiene Service Center, Okazaki, Aichi, Japan
- Kenji Ohya
- ORCiD
- Faculty of Applied Biological Sciences, Gifu University, Gifu, Gifu, Japan, United Graduate School of Veterinary Sciences, Gifu University, Gifu, Gifu, Japan
- Atsushi Ota
- Data Science Center, Division of Biological Science, Nara Institute of Science and Technology, Ikoma, Nara, Japan
- Yukiko Nishiuchi
- ORCiD
- Office of Academic Research and Industry-Government Collaboration, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan
- Hirokazu Yano
- ORCiD
- Graduate School of Life Sciences, Tohoku University, Sendai, Miyagi, Japan
- Kayoko Matsuo
- Kumamoto Prefectural Aso Public Health Center, Aso, Kumamoto, Japan
- Justice Opare Odoi
- ORCiD
- United Graduate School of Veterinary Sciences, Gifu University, Gifu, Gifu, Japan
- Shota Suganuma
- Faculty of Applied Biological Sciences, Gifu University, Gifu, Gifu, Japan
- Kotaro Sawai
- ORCiD
- Faculty of Applied Biological Sciences, Gifu University, Gifu, Gifu, Japan, Viral Disease and Epidemiology Research Division, National Institute of Animal Health, National Agriculture Research Organization, Tsukuba, Ibaraki, Japan
- Akemi Hasebe
- Toyama Prefectural Meat Inspection Center, Imizu, Toyama, Japan
- Tetsuo Asai
- ORCiD
- United Graduate School of Veterinary Sciences, Gifu University, Gifu, Gifu, Japan
- Tokuma Yanai
- ORCiD
- Faculty of Applied Biological Sciences, Gifu University, Gifu, Gifu, Japan, United Graduate School of Veterinary Sciences, Gifu University, Gifu, Gifu, Japan, Hiwa Natural History Museum, Shobara, Hiroshima, Japan
- Hideto Fukushi
- ORCiD
- Faculty of Applied Biological Sciences, Gifu University, Gifu, Gifu, Japan, United Graduate School of Veterinary Sciences, Gifu University, Gifu, Gifu, Japan
- Takayuki Wada
- ORCiD
- Graduate School of Human Life Science, Osaka City University, Osaka, Osaka, Japan
- Shiomi Yoshida
- ORCiD
- Clinical Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center, Sakai, Osaka, Japan
- Toshihiro Ito
- Laboratory of Proteome Research, Proteome Research Center, National Institutes of Biomedical Innovation, Health and Nutrition, Ibaraki, Osaka, Japan
- Kentaro Arikawa
- Department of Infectious Diseases, Kobe Institute of Health, Kobe, Hyogo, Japan
- Mikihiko Kawai
- ORCiD
- Graduate School of Human and Environmental Studies, Kyoto University, Kyoto, Kyoto, Japan
- Manabu Ato
- ORCiD
- Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, Higashimurayama, Tokyo, Japan
- Anthony D Baughn
- ORCiD
- Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, Minnesota, USA
- Tomotada Iwamoto
- ORCiD
- Department of Infectious Diseases, Kobe Institute of Health, Kobe, Hyogo, Japan
- Fumito Maruyama
- ORCiD
- Office of Academic Research and Industry-Government Collaboration, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan, Project Research Center for Holobiome and Built Environment (CHOBE), Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan, Scientific and Technological Bioresource Nucleus, Universidad de La Frontera, Temuco, Chile
Abstract
Mycobacterium avium subsp. hominissuis (MAH) is one of the most important agents causing non-tuberculosis mycobacterial infection in humans and pigs. There have been advances in genome analysis of MAH from human isolates, but studies of isolates from pigs are limited despite its potential source of infection to human. Here, we obtained 30 draft genome sequences of MAH from pigs reared in Japan. The 30 draft genomes were 4,848,678–5,620,788 bp in length, comprising 4652–5388 coding genes and 46–75 (median: 47) tRNAs. All isolates had restriction modification-associated genes and 185–222 predicted virulence genes. Two isolates had tRNA arrays and one isolate had a clustered regularly interspaced short palindromic repeat (CRISPR) region. Our results will be useful for evaluation of the ecology of MAH by providing a foundation for genome-based epidemiological studies.
