Transformation of low-grade follicular lymphoma with partial marginal zone differentiation: Two cases

Abstract

Two cases of low-grade follicular lymphoma, with marginal zone differentiation and/or with high proliferation rate in one of them, are reported with transformation into high grade B-cell and B-lymphoblastic lymphomas. The contribution of these features to the transforming process, although previously described, is infrequent, and has not been deciphered to date.

Keywords

• Follicular lymphoma
• high proliferation index
• high grade B-cell lymphoma
• transformation