Mechanical compression creates a quiescent muscle stem cell niche

Jiaxiang Tao; Mohammad Ikbal Choudhury; Debonil Maity; Taeki Kim; Sean X. Sun; Chen-Ming Fan

doi:10.1038/s42003-023-04411-2

Communications Biology (Jan 2023)

Mechanical compression creates a quiescent muscle stem cell niche

Jiaxiang Tao,
Mohammad Ikbal Choudhury,
Debonil Maity,
Taeki Kim,
Sean X. Sun,
Chen-Ming Fan

Affiliations

Jiaxiang Tao: Embryology Department, Carnegie Institution for Science
Mohammad Ikbal Choudhury: Department of Mechanical Engineering, Johns Hopkins University
Debonil Maity: Department of Mechanical Engineering, Johns Hopkins University
Taeki Kim: Department of Civil & Systems Engineering, Johns Hopkins University
Sean X. Sun: Department of Mechanical Engineering, Johns Hopkins University
Chen-Ming Fan: Embryology Department, Carnegie Institution for Science

DOI: https://doi.org/10.1038/s42003-023-04411-2
Journal volume & issue: Vol. 6, no. 1
pp. 1 – 12

Abstract

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Mechanical compression drives activated muscle stem cells (MuSCs) into a quiescent stem cell state providing insight into MuSC activity during injury-regeneration cycles.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal