A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria

Sandro Roier; Franz G. Zingl; Fatih Cakar; Sanel Durakovic; Paul Kohl; Thomas O. Eichmann; Lisa Klug; Bernhard Gadermaier; Katharina Weinzerl; Ruth Prassl; Achim Lass; Günther Daum; Joachim Reidl; Mario F. Feldman; Stefan Schild

doi:10.1038/ncomms10515

Nature Communications (Jan 2016)

A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria

Sandro Roier,
Franz G. Zingl,
Fatih Cakar,
Sanel Durakovic,
Paul Kohl,
Thomas O. Eichmann,
Lisa Klug,
Bernhard Gadermaier,
Katharina Weinzerl,
Ruth Prassl,
Achim Lass,
Günther Daum,
Joachim Reidl,
Mario F. Feldman,
Stefan Schild

Affiliations

Sandro Roier: Institute of Molecular Biosciences, University of Graz, NAWI Graz, BioTechMed-Graz
Franz G. Zingl: Institute of Molecular Biosciences, University of Graz, NAWI Graz, BioTechMed-Graz
Fatih Cakar: Institute of Molecular Biosciences, University of Graz, NAWI Graz, BioTechMed-Graz
Sanel Durakovic: Institute of Molecular Biosciences, University of Graz, NAWI Graz, BioTechMed-Graz
Paul Kohl: Institute of Molecular Biosciences, University of Graz, NAWI Graz, BioTechMed-Graz
Thomas O. Eichmann: Institute of Molecular Biosciences, University of Graz, NAWI Graz, BioTechMed-Graz
Lisa Klug: Institute of Biochemistry, Graz University of Technology, NAWI Graz, BioTechMed-Graz
Bernhard Gadermaier: Institute of Molecular Biosciences, University of Graz, NAWI Graz, BioTechMed-Graz
Katharina Weinzerl: Institute of Molecular Biosciences, University of Graz, NAWI Graz, BioTechMed-Graz
Ruth Prassl: Institute of Biophysics, Medical University of Graz, BioTechMed-Graz
Achim Lass: Institute of Molecular Biosciences, University of Graz, NAWI Graz, BioTechMed-Graz
Günther Daum: Institute of Biochemistry, Graz University of Technology, NAWI Graz, BioTechMed-Graz
Joachim Reidl: Institute of Molecular Biosciences, University of Graz, NAWI Graz, BioTechMed-Graz
Mario F. Feldman: Department of Biological Sciences, University of Alberta
Stefan Schild: Institute of Molecular Biosciences, University of Graz, NAWI Graz, BioTechMed-Graz

DOI: https://doi.org/10.1038/ncomms10515
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 13

Abstract

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Bacteria release outer membrane vesicles (OMVs) that play important roles in pathogenesis and intercellular interactions. Here, Roier et al. provide evidence supporting that phospholipid accumulation in the outer leaflet of the outer membrane participates in OMV formation in Gram-negative bacteria.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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