Endocervical Placental Site Trophoblastic Tumor: A Case Report

Abstract

Objective: We report the treatment of a patient with persistent gestational trophoblastic disease. Case Report: A 42-year-old woman, gravida 2, para 1, was initially diagnosed with choriocarcinoma from curettage specimens. She initially responded to aggressive chemotherapy but later was unresponsive. Subsequently, she underwent total abdominal hysterectomy; the resected uterus revealed a placental site trophoblastic tumor. Adjuvant chemotherapy was given. The serum human chorionic gonadotropin level progressively decreased to zero. The patient was alive and well at the time of writing. Conclusion: Chemotherapy-resistant persistent gestational trophoblastic disease may suggest placental site trophoblastic tumor. Surgery is the main treatment for placental site trophoblastic tumor.

Keywords

• placental site trophoblastic tumor
• surgery
• chemotherapy