Molbank (Apr 2014)

5-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl)-2-methyl-pentanoic Acid Methyl Ester

  • Kuan-Hua Chen,
  • Chang-Feng Dai,
  • Tsong-Long Hwang,
  • Ping-Jyun Sung

DOI
https://doi.org/10.3390/m822
Journal volume & issue
Vol. 2014, no. 2
p. M822

Abstract

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A natural diastereomeric mixture of 5-(6-hydroxy-2,5,7,8-tetramethyl-chroman-2-yl)-2-methyl-pentanoic acid methyl ester (1), was isolated from the soft coral Sinularia arborea. The structure of 1 was elucidated by spectroscopic methods and 1 displayed a significantly inhibitory effect on the generation of superoxide anion by human neutrophils.

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